課程資訊
課程名稱
 醫用高分子特論
Advanced Topics in Biomedical Polymers 
開課學期
 101-2 
授課對象
 工學院  醫學工程學研究所  
授課教師
 楊台鴻 
課號
 Biomed7013 
課程識別碼
 548 M0220 
班次
  
學分
 3 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期二1,2,3(8:10~11:10) 
上課地點
  
備註
 本課程中文授課,使用英文教科書。教室：基醫507。
總人數上限：30人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/1012Biomed7013 
課程簡介影片
 
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課程大綱
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課程概述

DEALS WITH ADVANCED TOPICS IN CURRENT BIOMEDICAL POLYMERS RESEARCH INCLUDING THE CELL-POLYMER INTERFACE,MOLECULAR ENGINEERING OF BIOMEDICAL POLYMERS,NANOSCALE BIOMEDICAL POLYMERS,HIERARCHICALLY ASSEMBLING POLYMERS,PROTEIN PEPTIDE DESIGN,BIOACTIVE POLYMERS,AND SURFACE SCIENCE.
EMPHASIS ON POLYMERS USED IN THE APPLICATIONS OF TISSUE ENGINEERING AND REGENERRATIVE MEDICINE.IT WELL BE COMPOSED OF BOTH DIDACTIC AND DISCUSSION/LITERATURE-BASED ACTIVITIES. 

課程目標
 TO UNDERSTAND THE INTERACTION OF CELL-BIOMATERIAL.
 
課程要求
 自動自發 
預期每週課後學習時數
  
Office Hours
 每週四 08:10~10:30 
指定閱讀
 BIOMEDICAL POLYMERS RESEARCH 
參考書目
 RELATED JOURNAL PAPERS 
評量方式
(僅供參考)
  
No.
項目
百分比
說明
1. 
 期中考 
50% 
  
2. 
 期末考 
50% 
  
 
課程進度
週次
日期
單元主題
第1週
 2/19  介紹醫用高分子特論課程大綱及講解Glycoprotein與Proteoglycan差別[核心能力7]  
第2週
 2/26  Immobilized Amines and Basic Amino Acids as Mimetic Heparin-
binding Domains for Cell Surface Proteoglycan-mediated Adhesion*
[核心能力7] 
第3週
 3/05  1.Role of cell shape in growth control 2.A scanning electron microscope study of cell adhesion and spreading in vitro[核心能力7] 
第4週
 3/12  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.[核心能力7] 
第5週
 3/19  Anchorage Dependence, Integrins,and Apotosis ADHESION AND SPREADING IN VITRO [核心能力7]  
第6週
 3/26  學生報告-探討實驗技術原理及應用 [核心能力2]  
第7週
 4/02  Role of the heparin binding domain of fibronectin in attachment and spreading of human bone-derived cells [核心能力7]  
第8週
 4/09  Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay [核心能力7]  
第9週
 4/16  1.Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis? 2.Enhanced cell survival of melanocyte spheroids in
serum starvation condition[核心能力7]  
第10週
 4/23  期中考 
第11週
 4/30  Behavior of embryonic rat cerebral cortical stem cells on the PVA and EVAL substrates[核心能力7] 
第12週
 5/07  1.Formation of melanocyte spheroids on the chitosan-coated surface
2.Enhanced cell survival of melanocyte spheroids in
serum starvation condition[核心能力7]  
第13週
 5/14  Proliferation and differentiation of neural stem cells on lysine–alanine
sequential polymer substrates[核心能力7]  
第14週
 5/21  The enhancement of submandibular gland
branch formation on chitosan membranes[核心能力7]  
第15週
 5/28  Regulation of ciliary differentiation of human respiratory epithelial cells by the
receptor for hyaluronan-mediated motility on hyaluronan-based biomaterials[核心能力7] 
第16週
 6/04  Induction of differentiation and mineralization in rat tooth germ cells on PVA
through inhibition of ERK1/2[核心能力7] 
第17週
 6/11  期末考